Sabrina Paganoni, MD, PhD, is the Robert H. Brown, Jr., PhilD, MD Endowed Chair in Neurology, Co-Director of the Neurological Research Institute at the Massachusetts General Hospital, and Associate Professor of PM&R at Harvard Medical School. Her research focuses on clinical trials and therapy development for ALS. She is the Principal Investigator of several clinical trials and has pioneered novel trial designs and partnership models to innovate clinical trial methodology in Neurology. She is a member of the National Academy of Medicine.